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Article

An aberrant cerebellar development in mice lacking matrix metalloproteinase-3.

Molecular neurobiology - 1 Feb 2012

Van Hove Inge, Verslegers Mieke, Buyens Tom, Delorme Nathalie, Lemmens Kim, Stroobants Stijn, Gantois Ilse, D'Hooge Rudi, Moons Lieve

Abstract excerpt

Cell-cell and cell-matrix interactions are necessary for neuronal patterning and brain wiring during development. Matrix metalloproteinases (MMPs) are proteolytic enzymes capable of remodelling the pericellular environment and regulating signaling pathways through cleavage of a large degradome. MMPs have been suggested to affect cerebellar development, but the specific role of different MMPs in cerebellar...

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PMID: 22108898
DOI: 10.1007/s12035-011-8215-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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