Article
Relationship between genetic polymorphisms of angiotensin-converting enzyme and methylenetetrahydrofolate reductase as risk factors for type 2 diabetes in Tunisian patients.
Clinical biochemistry - 1 Feb 2010
Mehri Sounira, Koubaa Nadia, Nakbi Amel, Hammami Sonia, Chaaba Raja, Mahjoub Sinda, Zouari Bechir, Abid Mohamed, Ben Arab Saida, Baudin Bruno, Hammami Mohamed
Abstract excerpt
BACKGROUND/AIMS: The role of methylenetetrahydrofolate reductase (MTHFR) and angiotensin-converting enzyme (ACE) gene polymorphisms as being risk factors for diabetes is still controversial. The aim was to investigate the distribution of ACE and MTHFR genotypes as well as to evaluate the role of plasmatic total homocysteine levels (tHcy) and ACE activity in Tunisian patients with type 2 diabetes mellitus (T2DM)....
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