Article
ALAD and APOE polymorphisms are associated with lead and mercury levels in Italian pregnant women and their newborns with adequate nutritional status of zinc and selenium.
Environmental research - 1 Mar 2023
Palir Neža, Stajnko Anja, Snoj Tratnik Janja, Mazej Darja, Briški Alenka Sešek, France-Štiglic Alenka, Rosolen Valentina, Mariuz Marika, Giordani Elisa, Barbone Fabio, Horvat Milena, Falnoga Ingrid
Abstract excerpt
The impacts of single-nucleotide polymorphisms (SNPs) in ALAD and VDR genes on Pb health effects and/or kinetics are inconclusive at low exposure levels, while studies including APOE SNPs are rare. In this study, we examined the associations of ALAD, VDR and APOE SNPs with exposure biomarkers of Pb and other trace elements (TEs) in Italian pregnant women (N = 873, aged 18-44 years) and their newborns (N = 619)...
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