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Article

The effect of the G1888A mutation of subgenotype A1 of hepatitis B virus on the translation of the core protein.

Virus research - 1 Jan 2012

Kimbi Gerald C, Kew Michael C, Kramvis Anna

Abstract excerpt

A distinctive characteristic of subgenotype A1 of hepatitis B virus is G1888A in the precore region. This transition introduces an out-of-frame AUG, creating an overlapping upstream open reading frame (uORF), terminating five nucleotides downstream from the core AUG. This uORF can potentially be translated into a seven amino acid peptide. In addition to stabilizing the encapsidation signal by forming a base pair...

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Identifiers

PMID: 22100339
DOI: 10.1016/j.virusres.2011.10.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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