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Article

The GM-CSF receptor utilizes β-catenin and Tcf4 to specify macrophage lineage differentiation.

Differentiation; research in biological diversity - 1 Jan 2012

Brown Anna L, Salerno Diana G, Sadras Teresa, Engler Grant A, Kok Chung H, Wilkinson Christopher R, Samaraweera Saumya E, Sadlon Timothy J, Perugini Michelle, Lewis Ian D, Gonda Thomas J, D'Andrea Richard J

Abstract excerpt

Granulocyte-macrophage colony stimulating factor (GM-CSF) promotes the growth, survival, differentiation and activation of normal myeloid cells and is essential for fully functional macrophage differentiation in vivo. To better understand the mechanisms by which growth factors control the balance between proliferation and self-renewal versus growth-suppression and differentiation we have used the bi-potent FDB1...

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Identifiers

PMID: 22099176
DOI: 10.1016/j.diff.2011.08.003
PMCID: PMC3394929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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