Article
Predictive value of early viral dynamics during peginterferon and ribavirin combination therapy based on genetic polymorphisms near the IL28B gene in patients infected with HCV genotype 1b.
Journal of medical virology - 1 Jan 2012
Toyoda Hidenori, Kumada Takashi, Tada Toshifumi, Hayashi Kazuhiko, Honda Takashi, Katano Yoshiaki, Goto Hidemi, Kawaguchi Takahisa, Murakami Yoshiki, Matsuda Fumihiko
Abstract excerpt
A study was carried out to determine whether early viral dynamics retain prediction of the outcome of peginterferon (PEG-IFN) and ribavirin combination therapy based on different genetic polymorphisms near the IL28B gene, the strongest baseline predictor of response to this therapy. A total of 272 patients infected with hepatitis C virus (HCV) genotype 1b were grouped according to genetic polymorphisms near the...
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