No impact of obesity susceptibility loci on weight regain after a lifestyle intervention in overweight children.

doi:10.1515/jpem-2013-0179

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Article

No impact of obesity susceptibility loci on weight regain after a lifestyle intervention in overweight children.

Journal of pediatric endocrinology & metabolism : JPEM - 1 Jan 2013

Hinney Anke, Wolters Barbara, Pütter Carolin, Grallert Harald, Illig Thomas, Hebebrand Johannes, Reinehr Thomas

Abstract excerpt

OBJECTIVE: An obesity risk allele at the NEGR1 locus was shown to be associated with weight regain after a lifestyle intervention in obese adults. Independent confirmation and studies in children are lacking. Therefore, we analyzed the impact of this and 11 additional obesity susceptibility loci on weight regain after a lifestyle intervention in overweight children. DESIGN AND METHODS: We longitudinally analyzed...