Article
Neurogenic and antineurogenic effects from modifications at the Notch locus.
Development (Cambridge, England) - 1 May 1990
Palka J, Schubiger M, Schwaninger H
Abstract excerpt
The best studied mutations at the Notch locus produce a neurogenic phenotype, with a massive overgrowth of the nervous system at the expense of epidermis. We report here that, in the development of the adult peripheral nervous system, the Abruptex alleles of Notch have the opposite phenotype, namely an underproduction of sensory organs or sensilla. This arises primarily not from an arrest of the lineages that...
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