Article
Defective neuroblast commitment in mutants of the achaete-scute complex and adjacent genes of D. melanogaster.
Neuron - 1 Jul 1990
Jiménez F, Campos-Ortega J A
Abstract excerpt
Loss of function mutations in genes of the achaete-scute complex (ASC) or in the gene vnd of D. melanogaster result in neural hypoplasia. Two types of defects contribute to the development of the neural hypoplasic phenotype: a lower than normal proportion of neuroblasts delaminate from the neuroectoderm, and there is abundant cell death in the neural primordium during later stages. In addition, we found that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.