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Article

Polymorphism of estrogen response element in TFF1 gene promoter is associated with an increased susceptibility to gastric cancer.

Gene - 15 Jan 2012

Moghanibashi Mehdi, Mohamadynejad Parisa, Rasekhi Maryam, Ghaderi Abbas, Mohammadianpanah Mohammad

Abstract excerpt

TFF1 is a cysteine-rich protein that forms a characteristic trefoil domain through disulfide bonds, which render it resistant to vigorous conditions and it involves in maintaining the integrity of the gastric mucosa. Decreased expression of TFF1 gene plays a role in the development of gastric cancer. We examined the association between the promoter polymorphisms of the TFF1 gene and the risk of development of...

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Source

Identifiers

PMID: 22093877
DOI: 10.1016/j.gene.2011.10.048

Genes

TFF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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