Article
Rapid identification of neuraminidase inhibitor resistance mutations in seasonal influenza virus A(H1N1), A(H1N1)2009, and A(H3N2) subtypes by melting point analysis.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Jul 2012
Redlberger-Fritz M, Aberle S W, Strassl R, Popow-Kraupp T
Abstract excerpt
The high mutation rate of influenza virus, combined with the increasing worldwide use of influenza virus-specific drugs, allows the selection of viruses that are resistant to the currently available antiviral medications. Therefore, reliable tests for the rapid detection of drug-resistant influenza virus strains are required. We evaluated the use of a procedure involving real-time polymerase chain reaction (PCR)...
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