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Article

Rapid molecular detection of the H275Y oseltamivir resistance gene mutation in circulating influenza A (H1N1) viruses.

Journal of virological methods - 1 Nov 2008

Carr Michael J, Sayre Naomi, Duffy Margaret, Connell Jeff, Hall William W

Abstract excerpt

In early 2008, drug susceptibility surveillance of influenza viruses in Europe revealed that some influenza A viruses (subtype H1N1) circulating during the winter season of 2007 and 2008 were resistant to the neuraminidase inhibitor, oseltamivir. This resistance arises due to a histidine to tyrosine substitution in the neuraminidase active site (H275Y in N1 nomenclature). Current methods to detect this mutation...

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Source

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Identifiers

PMID: 18718489
DOI: 10.1016/j.jviromet.2008.07.011
PMCID: PMC7112815

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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