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Article

A Two-Compartment Model of VEGF Distribution in the Mouse

8 Nov 2011

Abstract excerpt

Vascular endothelial growth factor (VEGF) is a key regulator of angiogenesis--the growth of new microvessels from existing microvasculature. Angiogenesis is a complex process involving numerous molecular species, and to better understand it, a systems biology approach is necessary. In vivo preclinical experiments in the area of angiogenesis are typically performed in mouse models; this includes drug development...

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PMID: 22087332
DOI: 10.1371/journal.pone.0027514

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