Article
Multi-scale mathematical modelling of tumour growth and microenvironments in anti-angiogenic therapy.
Biomedical engineering online - 28 Dec 2016
Cai Yan, Zhang Jie, Li Zhiyong
Abstract excerpt
BACKGROUND: Angiogenesis, a process of generation of new blood vessels from the pre-existing vasculature, has been demonstrated to be a basic prerequisite for sustainable growth and proliferation of tumour. Anti-angiogenic treatments show normalization of tumour vasculature and microenvironment at least transiently in both preclinical and clinical settings. METHODS: In this study, we proposed a multi-scale...
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