Article
Prognostic impact of morphologic and phenotypic features of childhood ALK-positive anaplastic large-cell lymphoma: results of the ALCL99 study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Dec 2011
Lamant Laurence, McCarthy Keith, d'Amore Emanuele, Klapper Wolfram, Nakagawa Atsuko, Fraga Maximo, Maldyk Jadwiga, Simonitsch-Klupp Ingrid, Oschlies Ilske, Delsol Georges, Mauguen Audrey, Brugières Laurence, Le Deley Marie-Cécile
Abstract excerpt
PURPOSE: The prognostic value of pathologic characteristics of childhood ALK-positive anaplastic large-cell lymphomas (ALCL), such as histologic subtypes, immunophenotype, and presence of the t(2;5) translocation or its variants, was assessed. PATIENTS AND METHODS: All 375 patients with systemic ALK-positive ALCL included in an international trial launched by the European Intergroup for Childhood Non-Hodgkin's...
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