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Article

ALK-Positive Lymphoma: A Single Disease With a Broad Spectrum of Morphology

15 Mar 1998

Abstract excerpt

The t(2;5)(p23;q35) translocation, associated with anaplastic large-cell lymphoma (ALCL), results in the expression of a chimeric NPM-ALK protein that can be detected by the ALK1 monoclonal antibody. This report describes the morphologic and phenotypic spectrum of 123 cases of lymphoma that all express ALK protein. The results provide strong evidence that the morphologic patterns of ALCL described in previous...

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Identifiers

PMID: 9490693
DOI: 10.1182/blood.v91.6.2076

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