Association study of nonsynonymous single nucleotide polymorphisms in schizophrenia.

doi:10.1016/j.biopsych.2011.09.032

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Article

Association study of nonsynonymous single nucleotide polymorphisms in schizophrenia.

Biological psychiatry - 15 Jan 2012

Carrera Noa, Arrojo Manuel, Sanjuán Julio, Ramos-Ríos Ramón, Paz Eduardo, Suárez-Rama Jose J, Páramo Mario, Agra Santiago, Brenlla Julio, Martínez Silvia, Rivero Olga, Collier David A, Palotie Aarno, Cichon Sven, Nöthen Markus M, Rietschel Marcella, Rujescu Dan, Stefansson Hreinn, Steinberg Stacy, Sigurdsson Engilbert, St Clair David, Tosato Sarah, Werge Thomas, Stefansson Kari, González Jose Carlos, Valero Joaquín, Gutiérrez-Zotes Alfonso, Labad Antonio, Martorell Lourdes, Vilella Elisabet, Carracedo Ángel, Costas Javier

Abstract excerpt

BACKGROUND: Genome-wide association studies using several hundred thousand anonymous markers present limited statistical power. Alternatively, association studies restricted to common nonsynonymous single nucleotide polymorphisms (nsSNPs) have the advantage of strongly reducing the multiple testing problem, while increasing the probability of testing functional single nucleotide polymorphisms (SNPs). METHODS: We...

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PMID: 22078303
DOI: 10.1016/j.biopsych.2011.09.032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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