Article
Longitudinal changes in PON1 activities, PON1 phenotype distribution and oxidative status throughout normal pregnancy.
Reproductive toxicology (Elmsford, N.Y.) - 1 Jan 2012
Stefanović Aleksandra, Ardalic Daniela, Kotur-Stevuljević Jelena, Vujović Ana, Spasic Slavica, Spasojević-Kalimanovska Vesna, Jelic-Ivanovic Zorana, Mandic-Markovic Vesna, Mikovic Zeljko, Cerovic Nikola
Abstract excerpt
The purpose of the present study was to determine changes in plasma paraoxonase-1 activity (an indicator of paraoxonase phenotype) throughout normal pregnancy and its relationship with maternal oxidative stress status. The frequencies of the paraoxonase-1 phenotype in the studied population were determined using a two-substrate (paraoxon/diazoxon) activity method. As a parameter of oxidative stress status we...
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