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Article

Genome-wide association study identifies a novel maternal gene × stress interaction associated with spontaneous preterm birth.

Pediatric research - 1 May 2021

Hong Xiumei, Surkan Pamela J, Zhang Boyang, Keiser Amaris, Ji Yuelong, Ji Hongkai, Burd Irina, Bustamante-Helfrich Blandine, Ogunwole S Michelle, Tang Wan-Yee, Liu Li, Pearson Colleen, Cerda Sandra, Zuckerman Barry, Hao Lingxin, Wang Xiaobin

Abstract excerpt

BACKGROUND: Maternal stress is potentially a modifiable risk factor for spontaneous preterm birth (sPTB). However, epidemiologic findings on the maternal stress-sPTB relationship have been inconsistent. METHODS: To investigate whether the maternal stress-sPTB associations may be modified by genetic susceptibility, we performed genome-wide gene × stress interaction analyses in 1490 African-American women from the...

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Identifiers

PMID: 32726798
DOI: 10.1038/s41390-020-1093-1
PMCID: PMC8400921

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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