Article
Association of galectin-3 expression with melanoma progression and prognosis.
European journal of cancer (Oxford, England : 1990) - 1 Apr 2012
Brown Ewan R, Doig Tamasin, Anderson Niall, Brenn Thomas, Doherty Val, Xu Yan, Bartlett John M S, Smyth John F, Melton David W
Abstract excerpt
AIMS: Galectin-3 plays an important role in adhesion, proliferation, differentiation, angiogenesis and metastasis in multiple tumours. To investigate the role of galectin-3 in melanoma pathogenesis we examined the expression of galectin-3 in melanocytic lesions and analysed the correlation between galectin-3 expression and clinicopathologic factors including patient survival and BRAF mutation status. METHODS: We...
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