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Article

PAX3 expression in normal skin melanocytes and melanocytic lesions (naevi and melanomas).

PloS one - 22 Apr 2010

Medic Sandra, Ziman Mel

Abstract excerpt

BACKGROUND: Cutaneous Malignant Melanoma is an aggressive form of skin cancer, arising in cutaneous melanocytes. The transcription factor PAX3 regulates melanocyte specification from neural crest cells during development but expression in differentiated melanocytes is uncertain. By contrast it is frequently found in melanomas and naevi and is a marker for melanoma staging and detection. In this study we analysed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20421967
DOI: 10.1371/journal.pone.0009977
PMCID: PMC2858648

Genes

PAX3
HES1
MCAM
MITF
MLANA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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