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Article

Genomic aberrations in pediatric diffuse intrinsic pontine gliomas

7 Nov 2011

Abstract excerpt

Diagnostic biopsy is not routinely performed for children with diffuse intrinsic pontine glioma (DIPG). Consequently, our understanding of DIPG biology is hindered by limited tissue availability. We performed comparative genomic hybridization (CGH) on autopsy specimens to examine the feasibility of determining DNA genomic copy number aberrations on formalin-fixed, paraffin-embedded (FFPE) blocks. Histology on...

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PMID: 22064882
DOI: 10.1093/neuonc/nor190

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