Article
Novel association of acid phosphatase locus 1*C allele with systemic lupus erythematosus.
Human immunology - 1 Jan 2012
Teruel María, Martin Jose-Ezequiel, Ortego-Centeno Norberto, Jiménez-Alonso Juan, Sánchez-Román Julio, de Ramón Enrique, Gonzalez-Escribano M Francisca, Pons-Estel Bernardo A, D'Alfonso Sandra, Sebastiani Gian Domenico, Witte Torsten, Bottini Nunzio, González-Gay Miguel A, Alarcón-Riquelme Marta E, Martin Javier
Abstract excerpt
The red cell acid phosphatase (ACP1) gene, which encodes a low-molecular-weight phosphotyrosine phosphatase, has been suggested as a common genetic factor of autoimmunity. In the present study, we aim to investigate the possible association of ACP1 with the susceptibility of systemic lupus erythematosus (SLE). A total of 1,546 SLE patients and 1,947 healthy individuals from 4 Caucasians populations were included...
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