Comparative pathogenicity of a wild-type strain and respiratory mutants of Candida albicans in mice.

Abstract excerpt

The pathogenicity of a parent wild-type strain and three respiratory mutants of Candida albicans was examined in intravenously infected mice. The wild-type strain K grew well in the kidney and caused severe candidosis, and the 21-day LD50 value was 7.2 x 10(6) cells/mouse. A mutant with a low rate of respiration (KRD-8) whose growth rate in vitro was somewhat lower than that of the wild type, produced germ tubes...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Body Weight
• Share to Candida albicans