Primary structure requirements for the maturation in vivo of penicillin acylase from Escherichia coli ATCC 11105.

doi:10.1111/j.1432-1033.1990.tb19207.x

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Article

Primary structure requirements for the maturation in vivo of penicillin acylase from Escherichia coli ATCC 11105.

European journal of biochemistry - 28 Aug 1990

Sizmann D, Keilmann C, Böck A

Abstract excerpt

The two constituent subunits of the enzyme penicillin acylase from Escherichia coli strain ATCC 11105 are derived from a single precursor polypeptide by post-translational processing. Mutant penicillin acylase precursors were constructed carrying insertions and deletions in various domains and they were analysed for their processing behaviour. It was found that an endopeptide region of appropriate size and an...

Topics

Amidohydrolases
Amino Acid Sequence
Base Sequence
Enterobacteriaceae
Escherichia coli
Gene Expression
Genes, Bacterial
Gram-Negative Bacteria
Molecular Sequence Data
Mutation
Penicillin Amidase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Peptides

Plasmids

Protein Conformation

Protein Processing, Post-Translational

Protein Sorting Signals

Pseudomonas

Source

Open in PubMed

Identifiers

PMID: 2205499
DOI: 10.1111/j.1432-1033.1990.tb19207.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2205499-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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