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Article

Regulation of chemotropic guidance of nerve growth cones by microRNA

3 Nov 2011

Abstract excerpt

BACKGROUND: The small non-coding microRNAs play an important role in development by regulating protein translation, but their involvement in axon guidance is unknown. Here, we investigated the role of microRNA-134 (miR-134) in chemotropic guidance of nerve growth cones. RESULTS: We found that miR-134 is highly expressed in the neural tube of Xenopus embryos. Fluorescent in situ hybridization also showed that...

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PMID: 22051374
DOI: 10.1186/1756-6606-4-40

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