Article
Neuropilin-1a is involved in trunk motor axon outgrowth in embryonic zebrafish.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Nov 2005
Feldner Julia, Becker Thomas, Goishi Katsutoshi, Schweitzer Jörn, Lee Percy, Schachner Melitta, Klagsbrun Michael, Becker Catherina G
Abstract excerpt
Neuropilin-1, a receptor for axon-repellent semaphorins and vascular endothelial growth factor (VEGF), functions both in angiogenesis and axon growth. Here, we show strong expression of neuropilin-1a in primary motor neurons in the trunk of embryonic zebrafish. Reducing the expression of neuropilin-1a using antisense morpholino oligonucleotides induced aberrant branching of motor nerves, additional exit points of...
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