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Article

Netrin-1-induced local β-actin synthesis and growth cone guidance requires zipcode binding protein 1.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 6 Jul 2011

Welshhans Kristy, Bassell Gary J

Abstract excerpt

Local β-actin synthesis in growth cones of developing axons plays an important role in growth cone steering; however, the mRNA binding proteins required for this process are unknown. Here we used Zbp1/Imp1(-/)(-) mice to test the hypothesis that zipcode binding protein 1 (ZBP1) is required for the regulation of β-actin mRNA transport and local translation underlying growth cone guidance. To address the biological...

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Source

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Identifiers

PMID: 21734271
DOI: 10.1523/JNEUROSCI.0166-11.2011
PMCID: PMC3137872

Genes

ZBP1
BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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