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Article

The<i>In Vivo</i>Expression of Radiation-Induced Chromosomal Instability Has an Inflammatory Mechanism

3 Nov 2011

Abstract excerpt

Ionizing radiation is unequivocally leukemogenic and carcinogenic, and this is generally attributed to DNA damage arising as a consequence of deposition of energy in the cell nucleus at the time of exposure. However, nontargeted effects, in which DNA damage is produced in nonirradiated cells as a consequence of cell signaling processes, indicate additional mechanisms. Radiation-induced chromosomal instability, a...

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PMID: 22050452
DOI: 10.1667/rr2793.1

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