Article
A systems biology approach to multicellular and multi-generational radiation responses.
Mutation research - 11 May 2006
Barcellos-Hoff Mary Helen, Costes Sylvain V
Abstract excerpt
Recent studies have highlighted crosstalk between irradiated cells and non-irradiated bystander cells and have uncovered high-frequency phenotypes of genomic instability in the progeny of irradiated cells that cannot be solely explained by radiation-induced mutation. It is difficult to explain these multicellular and multi-generational phenomena using the current paradigm of radiation biology. Radiation-induced...
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