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NF-κB as a key player in regulation of cellular radiation responses and identification of radiation countermeasures

31 Mar 2015

Abstract excerpt

Nuclear factor (NF)-κB is a transcription factor that plays significant role in immunity, cellular survival and inhibition of apoptosis, through the induction of genetic networks. Depending on the stimulus and the cell type, the members of NF-κB related family (RelA, c-Rel, RelB, p50, and p52), forms different combinations of homo and hetero-dimers. The activated complexes (Es) translocate into the nucleus and...

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PMID: 32309561
DOI: 10.15190/d.2015.27

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