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Article

Site-specific structural analysis of a yeast prion strain with species-specific seeding activity.

Prion - 1 Jan 2000

Marcelino-Cruz Anna Marie, Bhattacharya Moumita, Anselmo Aaron C, Tessier Peter M

Abstract excerpt

Prion proteins misfold and aggregate into multiple infectious strain variants that possess unique abilities to overcome prion species barriers, yet the structural basis for the species-specific infectivities of prion strains is poorly understood. Therefore, we have investigated the site-specific structural properties of a promiscuous chimeric form of the yeast prion Sup35 from Saccharomyces cerevisiae and Candida...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22048721
DOI: 10.4161/pri.5.3.16694
PMCID: PMC3226048

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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