Article
Synovial expression of Th17-related and cancer-associated genes is regulated by the arthritis severity locus Cia10.
Genes and immunity - 1 Apr 2012
Jenkins E, Brenner M, Laragione T, Gulko P S
Abstract excerpt
We have previously identified Cia10 as an arthritis severity and articular damage quantitative trait locus. In this study, we used Illumina RatRef-12 microarrays to analyze the expression of 21,922 genes in synovial tissues from arthritis-susceptible DA and arthritis-protected DA.ACI(Cia10) congenics with pristane-induced arthritis. 310 genes had significantly different expression. The genes upregulated in DA,...
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