Article
Micro RNA -214,-150,-146a and-125b target Huntingtin gene.
RNA biology - 1 Jan 2000
Sinha Mithun, Ghose Jayeeta, Bhattarcharyya Nitai P
Abstract excerpt
We observed earlier that expressions of several micro RNAs (miRNAs) are altered in a cell model of Huntington's disease (HD). As genes involved in different neurodegenerative diseases are targeted by miRNAs, we searched databases to find out whether Huntingtin gene (HTT), mutation to which causes HD, is a target of any miRNA. Among many miRNAs that are predicted to target HTT, we showed using various experimental...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
