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Article

Altered microRNA regulation in Huntington's disease models.

Experimental neurology - 1 Jan 2011

Lee Soon-Tae, Chu Kon, Im Woo-Seok, Yoon Hye-Jin, Im Ji-Yeon, Park Jung-Eun, Park Ki-Ho, Jung Keun-Hwa, Lee Sang Kun, Kim Manho, Roh Jae-Kyu

Abstract excerpt

Huntington's disease (HD) is a genetic neurodegenerative disease caused by abnormal CAG expansion. MicroRNAs (miRNAs) are short RNA molecules regulating gene expression, and are implicated in a variety of diseases including HD. However, the profiles and regulation of miRNAs in HD are not fully understood. Here, we analyzed the miRNA expression and miRNA regulators in two transgenic models of HD, YAC128 and R6/2...

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Identifiers

PMID: 21035445
DOI: 10.1016/j.expneurol.2010.10.012

Genes

DGCR8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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