Article
Analysis of mutations in the integration function of Moloney murine leukemia virus: effects on DNA binding and cutting.
Journal of virology - 1 Oct 1990
Roth M J, Schwartzberg P, Tanese N, Goff S P
Abstract excerpt
The 3' terminus of the pol gene of Moloney murine leukemia virus encodes the integration (IN) protein, required for the establishment of the integrated provirus. A series of six linker insertion mutations and two single-base substitutions were generated within the region encoding the IN protein....
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Southern
- Cell Line
- Cell Transformation, Viral
- DNA Nucleotidyltransferases
- DNA Replication
- DNA, Viral
- DNA-Binding Proteins
- Genes, pol
- Integrases
- Lysogeny
- Molecular Sequence Data
- Moloney murine leukemia virus
- Mutation
- Restriction Mapping