Sequence-specific binding of DNA by the Moloney murine leukemia virus integrase protein.

doi:10.1128/JVI.64.6.2796-2801.1990

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Article

Sequence-specific binding of DNA by the Moloney murine leukemia virus integrase protein.

Journal of virology - 1 Jun 1990

Krogstad P A, Champoux J J

Abstract excerpt

Genetic studies have indicated that integration of retroviral DNA into the host genome depends on the presence of the inverted repeats at the free termini of the long terminal repeats on the unintegrated DNA and on the product of the 3' end of the pol gene (the integrase [IN] protein). While the...

Topics

Base Sequence
Cloning, Molecular
DNA Nucleotidyltransferases
DNA, Viral
DNA-Binding Proteins
Escherichia coli
Immunoblotting
Integrases
Molecular Sequence Data
Moloney murine leukemia virus
Mutation
Oligonucleotide Probes
Plasmids
Recombinant Proteins

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