Article
The secreted aspartate proteinase of Candida albicans: physiology of secretion and virulence of a proteinase-deficient mutant.
Journal of general microbiology - 1 Apr 1990
Ross I K, De Bernardis F, Emerson G W, Cassone A, Sullivan P A
Abstract excerpt
It was established that Candida albicans grew rapidly in a simple medium containing yeast extract (0.2%, w/v) plus glucose (2%, w/v). These cultures were in or near to a state of nitrogen limitation and the concentration of secreted aspartate proteinase increased rapidly (within 3-4 h) on additio...
Topics
- Animals
- Aspartic Acid Endopeptidases
- Candida albicans
- Candidiasis
- Endopeptidases
- Female
- Gene Expression
- Lethal Dose 50
- Mice
- Mice, Inbred Strains
- Mutation
- Virulence
