Article
Evolutionary conserved longevity genes and human cognitive abilities in elderly cohorts.
European journal of human genetics : EJHG - 1 Mar 2012
Lopez Lorna M, Harris Sarah E, Luciano Michelle, Liewald Dave, Davies Gail, Gow Alan J, Tenesa Albert, Payton Antony, Ke Xiayi, Whalley Lawrence J, Fox Helen, Haggerty Paul, Ollier William, Pickles Andrew, Porteous David J, Horan Michael A, Pendleton Neil, Starr John M, Deary Ian J
Abstract excerpt
Genetic influences have an important role in the ageing process. The genetic factors that influence success in bodily ageing may also contribute to the successful ageing of cognitive abilities. A comparative genomics approach found longevity genes conserved between yeast Saccharomyces cerevisiae and nematode Caenorhabditis elegans. We hypothesised that these longevity genes influence variance in cognitive ability...
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