Article
α-Catenin promotes dermal fibroblasts proliferation and migration during wound healing via FAK/YAP activation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 31 Jan 2024
Wang Nan, Xu Xiejun, Guan Fangqian, Zheng Yeyi, Shou Yanni, Xu Tianpeng, Shen Guoxiu, Chen Hui, Lin Yifan, Cong Weitao, Jin Litai, Zhu Zhongxin
Abstract excerpt
Skin wound healing is a complex and organized biological process, and the dermal fibroblasts play a crucial role. α-Catenin is known to be involved in regulating various cellular signals, and its role in wound healing remains unclear. Here, we have identified the pivotal role of the α-catenin/FAK/YAP signaling axis in the proliferation and migration of dermal fibroblasts, which contributes to the process of skin...
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