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Article

Regulation of murine hematopoietic stem cell quiescence by Dmtf1

29 Oct 2011

Abstract excerpt

The cell-cycle status of hematopoietic stem cells (HSCs) is tightly regulated, most likely to balance maintenance of stem-cell status through quiescence and expansion/differentiation of the hematopoietic system. Tumor-suppressor genes (TSGs), with their cell cycle-regulatory functions, play important roles in HSC regulation. The cyclin-D binding myb-like transcription factor 1 (Dmtf1) was recently recognized as a...

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PMID: 22039255
DOI: 10.1182/blood-2011-05-349084

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