Article
The impact of platelet membrane glycoprotein Ib alpha and Ia/IIa polymorphisms on the risk of thrombosis in the antiphospholipid syndrome.
Thrombosis research - 1 Apr 2012
Yonal Ipek, Hindilerden Fehmi, Hancer Veysel Sabri, Artim-Esen Bahar, Daglar Aynur, Akadam Basak, Nalcaci Meliha, Diz-Kucukkaya Reyhan
Abstract excerpt
BACKGROUND: Pathogenesis of thrombus formation in antiphospholipid syndrome (APS) is not clear. Platelet membrane glycoprotein (GP) receptors play important roles in development of thrombosis. OBJECTIVES: We investigated the association between development of thrombosis in APS and polymorphisms of GPIb alpha variable number of tandem repeats (VNTR), Kozak, and GPIa C807T. Patients/Methods Sixty patients with APS...
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