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Article

P-selectin glycoprotein ligand-1 VNTR polymorphisms and risk of thrombosis in the antiphospholipid syndrome.

Annals of the rheumatic diseases - 1 Oct 2007

Diz-Kucukkaya Reyhan, Inanc Murat, Afshar-Kharghan Vahid, Zhang Q Ed, López José A, Pekcelen Yuksel

Abstract excerpt

OBJECTIVES: Antiphospholipid antibodies (aPLA) have been shown to enhance thrombus formation by increasing the expression of adhesive receptors such as P-selectin on endothelial cells. The P-selectin counter-receptor on leucocytes is P-selectin glycoprotein ligand-1 (PSGL-1). We have previously described a variable number of tandem repeats (VNTR) polymorphism in the mucin-like region of PSGL-1, with three...

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Identifiers

PMID: 17545190
DOI: 10.1136/ard.2007.075945
PMCID: PMC1994305

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Source receipt: pubmed, retrieved 7 Sept 2026.

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