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Article

Interactions of regulated and deregulated forms of the sigma54 holoenzyme with heteroduplex promoter DNA.

Nucleic acids research - 15 Feb 2002

Cannon Wendy, Wigneshweraraj Siva R, Buck Martin

Abstract excerpt

The bacterial sigma54 RNA polymerase holoenzyme binds to promoters as a stable closed complex that is silent for transcription unless acted upon by an enhancer-bound activator protein. Using DNA binding and transcription assays the ability of the enhancer-dependent sigma54 holoenzyme to interact with promoter DNA containing various regions of heteroduplex from -12 to -1 was assessed. Different DNA regions...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11842099
DOI: 10.1093/nar/30.4.886
PMCID: PMC100350

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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