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Article

Analysis of Transcriptome Complexity Through RNA Sequencing in Normal and Failing Murine Hearts

28 Oct 2011

Abstract excerpt

RATIONALE: Accurate and comprehensive de novo transcriptome profiling in heart is a central issue to better understand cardiac physiology and diseases. Although significant progress has been made in genome-wide profiling for quantitative changes in cardiac gene expression, current knowledge offers limited insights to the total complexity in cardiac transcriptome at individual exon level. OBJECTIVE: To develop...

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PMID: 22034492
DOI: 10.1161/circresaha.111.249433

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