Article
Susceptibility variants on chromosome 7p21.1 suggest HDAC9 as a new candidate gene for male-pattern baldness.
The British journal of dermatology - 1 Dec 2011
Brockschmidt F F, Heilmann S, Ellis J A, Eigelshoven S, Hanneken S, Herold C, Moebus S, Alblas M A, Lippke B, Kluck N, Priebe L, Degenhardt F A, Jamra R A, Meesters C, Jöckel K-H, Erbel R, Harrap S, Schumacher J, Fröhlich H, Kruse R, Hillmer A M, Becker T, Nöthen M M
Abstract excerpt
BACKGROUND: Male-pattern baldness (androgenetic alopecia, AGA) is the most common form of hair loss among humans. Research has shown that it is caused by genetic factors. Numerous studies have unequivocally identified two major genetic risk loci for AGA: the X-chromosomal AR/EDA2R locus, and the PAX1/FOXA2 locus on chromosome 20. OBJECTIVES: To identify further candidate genes for AGA, and thus gain further...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.