Article
Evidence for a polygenic contribution to androgenetic alopecia.
The British journal of dermatology - 1 Oct 2013
Heilmann S, Brockschmidt F F, Hillmer A M, Hanneken S, Eigelshoven S, Ludwig K U, Herold C, Mangold E, Becker T, Kruse R, Knapp M, Nöthen M M
Abstract excerpt
BACKGROUND: Male pattern baldness (androgenetic alopecia, AGA) is a highly heritable trait and the most common form of hair loss in humans. Eight genome-wide significant risk loci for AGA have been identified. OBJECTIVES: To determine whether a polygenic component contributes to the genetic risk for AGA. METHODS: This study used a German case-control sample for AGA, which comprised 581 severely affected patients...
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