Article
EDA2R is associated with androgenetic alopecia.
The Journal of investigative dermatology - 1 Sept 2008
Prodi Dionigio Antonio, Pirastu Nicola, Maninchedda Giuseppe, Sassu Alessandro, Picciau Andrea, Palmas Maria Antonietta, Mossa Alessandra, Persico Ivana, Adamo Mauro, Angius Andrea, Pirastu Mario
Abstract excerpt
Androgenetic alopecia (AGA) is a common heritable polygenic disorder whose genetics is not fully understood, even though it seems to be X-linked. We carried out an epidemiological survey for AGA on 9,000 people from 8 isolated villages of a secluded region of Sardinia (Ogliastra), and identified a large cohort of affected individuals. We genotyped 200 cases and 200 controls (mean kinship 0.001) with the 500k chip...
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