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Article

Structural studies on aldolase isozymes through protein engineering.

Progress in clinical and biological research - 1 Jan 1990

Takasaki Y, Kitajima Y, Takahashi I, Sakakibara M, Mukai T, Hori K

Abstract excerpt

Enzymatic studies on aldolase isozymes have been carried out by techniques of protein engineering. Site-directed mutagenesis helps us to verify the roles of amino acid residues in catalytic reactions. Chimeric fusion proteins give us information about the regions which specify the characteristics of the isozymes. The results are: (1) In aldolase A, COOH terminal Tyr and Lys-107 residues play important roles in...

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PMID: 2203067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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