Article
Protein engineering of bacterial alpha-amylases.
Biochimica et biophysica acta - 29 Dec 2000
Nielsen J E, Borchert T V
Abstract excerpt
alpha-Amylases constitute a very diverse family of glycosyl hydrolases that cleave alpha1-->4 linkages in amylose and related polymers. Recent structural and mutagenic studies of archeael, mammalian and bacterial alpha-amylases have resulted in a wealth of information on the catalytic mechanism and on the structural features of this enzyme class. Because of their high thermo-stability, the Bacillus alpha-amylases...
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